KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
10.3
Human Site:
S1068
Identified Species:
17.44
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1068
E
D
D
D
D
D
D
S
D
D
R
D
E
S
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P941
P
G
R
P
G
T
K
P
P
K
R
D
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
S1076
D
D
D
D
D
E
D
S
E
D
Q
D
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1110
E
D
D
N
E
A
D
S
D
G
Q
I
D
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
D1063
D
D
E
E
D
E
D
D
D
E
D
E
E
D
E
Frog
Xenopus laevis
Q66J90
1938
216239
S1012
G
S
V
S
A
L
S
S
K
K
R
L
Y
G
E
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
E994
S
S
G
K
D
L
E
E
E
D
E
K
K
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
T894
E
S
D
S
K
S
H
T
S
G
L
N
S
K
R
Honey Bee
Apis mellifera
XP_395451
1406
159180
G660
G
F
N
Y
D
G
F
G
L
G
I
R
A
S
M
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
V761
A
I
A
R
T
P
I
V
K
K
C
K
K
R
M
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
A1014
Q
M
M
P
P
S
S
A
G
N
A
V
Q
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
H567
S
S
E
D
H
R
R
H
S
Y
G
S
E
K
R
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
0
73.3
N.A.
46.6
N.A.
N.A.
0
40
20
26.6
N.A.
13.3
13.3
0
0
P-Site Similarity:
100
20
0
100
N.A.
80
N.A.
N.A.
0
80
20
46.6
N.A.
26.6
20
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
0
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
15
29
29
22
36
8
29
8
22
22
8
22
8
8
8
% D
% Glu:
22
0
15
8
8
15
8
8
15
8
8
8
36
8
36
% E
% Phe:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
15
8
8
0
8
8
0
8
8
22
8
0
0
8
0
% G
% His:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
8
8
0
0
0
% I
% Lys:
0
0
0
8
8
0
8
0
15
22
0
15
15
15
0
% K
% Leu:
0
0
0
0
0
15
0
0
8
0
8
8
0
0
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
15
% M
% Asn:
0
0
8
8
0
0
0
0
0
8
0
8
0
0
8
% N
% Pro:
8
0
0
15
8
8
0
8
8
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
15
0
8
0
0
% Q
% Arg:
0
0
8
8
0
8
8
0
0
0
22
8
0
8
22
% R
% Ser:
15
29
0
15
0
15
15
29
15
0
0
8
8
36
0
% S
% Thr:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _